Birth Defects from Anti Depressants - Personal Injury Legal Blogs Posted by Attorneys -

Birth Defects from Anti Depressants

Depression hurts…or so says the TV commercial. However, what hurts more are birth defects from anti depressants.


Like most studies and opinions, conclusions are contradictory. Take for instance this study by the New England Journal of Medicine in 2007: The study assessed associations between first-trimester maternal use of anti depressants and the risk of birth defects among 9,849 infants with and 5,860 infants without birth defects participating in the Slone Epidemiology Center Birth Defects Study.


Birth defects risks were not significantly increased with anti depressants although there were possible birth defects from the anti depressants Paxil and Zoloft.


More recent than 2007, elevated risks of birth defects overall, as well as elevated risks of omphalocele, craniosynostosis, and congenital heart defects,  have been reported in association with the use of anti depressants. One study specifically identified Paxil as increasing the risk of omphalocele, and three have associated Paxil with congenital heart defects. None of these studies considered cardiac birth defect risks in relation to other specific anti depressants.


Birth defects                                          Anti depressants

Neural tube defects                          Zoloft, SSRIs/general          

PPHN, coarctation of aorta                Celexa, Lexapro, Paxil, Prozac, Symbyax,Zoloft 

Septal heart defects, PS                    Paxil, Wellbutrin


While most doctors argue that the risk of birth defects from anti depressants is rare – if your baby suffers a birth defect because you took anti depressants while pregnant – the problem is not rare or small; the problem is overwhelming to you.





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